Biopolymers and cell, 1996, V.12, N 6 , P.63-68 Download full in ukrainian, pdf (172 kb)

G.D.Telegeev., M.V.Dybkov., M.V.Bozhko, N.M.Tretiak, S.S.Maliuta

MOLECULAR-BIOLOGY APPROACHES TO DETECTION OF PHILADELPHIA CHROMOSOME IN PATIENTS WITH LEUKEMIA.

The data of detection of philadelphia chromosome in patients with CML and ALL are presented. Two approaches was applied: the first - when 5'and 3' bcr genomic probes were used, the second - when two steps PCR whis specific primers was evaluated. The l ast one is more preferable for clinic accomodation. Some questions of Ph' leukemias etiology are also discussed.


., 1996, .12, N.6 .63-68.

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